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Management of relapsed or refractory Hodgkin lymphoma with second-generation antibody-drug conjugates: focus on brentuximab vedotin
Brentuximab vedotin (Adcetris, Seattle Genetics) is an antibody-drug conjugate (ADC) that joins an anti-CD 30 monoclonal antibody with the anti-tubulin agent monomethyl auristatin E, via a dipeptide linker. It has demonstrated significant activity in CD 30-positive lymphomas and is currently approve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4029876/ https://ncbi.nlm.nih.gov/pubmed/24258497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-013-0077-7 |
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