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Role of brentuximab vedotin in the treatment of relapsed or refractory Hodgkin lymphoma

Brentuximab vedotin (BV) is an antibody-drug conjugate that targets CD30-positive malignancies via an anti-CD30 monoclonal antibody linked to monomethyl auristatin E, a microtubule-disrupting agent, by a protease-cleavable linker. BV has received accelerated approval from the US Food and Drug Admini...

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Detalhes bibliográficos
Main Authors: Siddiqi, Tanya, Thomas, Sandra H, Chen, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959807/
https://ncbi.nlm.nih.gov/pubmed/24672256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S57700
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