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Role of brentuximab vedotin in the treatment of relapsed or refractory Hodgkin lymphoma
Brentuximab vedotin (BV) is an antibody-drug conjugate that targets CD30-positive malignancies via an anti-CD30 monoclonal antibody linked to monomethyl auristatin E, a microtubule-disrupting agent, by a protease-cleavable linker. BV has received accelerated approval from the US Food and Drug Admini...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Dove Medical Press
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959807/ https://ncbi.nlm.nih.gov/pubmed/24672256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S57700 |
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