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Loss of Synaptic Connectivity, Particularly in Second Order Neurons Is a Key Feature of Diabetic Retinal Neuropathy in the Ins2(Akita) Mouse

Retinal neurodegeneration is a key component of diabetic retinopathy (DR), although the detailed neuronal damage remains ill-defined. Recent evidence suggests that in addition to amacrine and ganglion cell, diabetes may also impact on other retinal neurons. In this study, we examined retinal degener...

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Bibliografiske detaljer
Main Authors: Hombrebueno, Jose R., Chen, Mei, Penalva, Rosana G., Xu, Heping
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029784/
https://ncbi.nlm.nih.gov/pubmed/24848689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097970
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