Changes of peripheral TGF-β1 depend on monocytes-derived macrophages in Huntington disease

BACKGROUND: Huntington Disease (HD) is a neurodegenerative disorder resulting from the expansion of polyglutamine stretch in the huntingtin protein (Htt). Mutant HTT (mHtt) leads to progressive impairment of several molecular pathways that have been linked to disease pathogenesis. Defects in the pro...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Di Pardo, Alba, Alberti, Silvia, Maglione, Vittorio, Amico, Enrico, Cortes, Etty P, Elifani, Francesca, Battaglia, Giuseppe, Busceti, Carla L, Nicoletti, Ferdinando, Vonsattel, Jean Paul G, Squitieri, Ferdinando
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2013
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029620/
https://ncbi.nlm.nih.gov/pubmed/24330808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-55
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