Changes of peripheral TGF-β1 depend on monocytes-derived macrophages in Huntington disease

BACKGROUND: Huntington Disease (HD) is a neurodegenerative disorder resulting from the expansion of polyglutamine stretch in the huntingtin protein (Htt). Mutant HTT (mHtt) leads to progressive impairment of several molecular pathways that have been linked to disease pathogenesis. Defects in the pro...

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Detalhes bibliográficos
Main Authors: Di Pardo, Alba, Alberti, Silvia, Maglione, Vittorio, Amico, Enrico, Cortes, Etty P, Elifani, Francesca, Battaglia, Giuseppe, Busceti, Carla L, Nicoletti, Ferdinando, Vonsattel, Jean Paul G, Squitieri, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029620/
https://ncbi.nlm.nih.gov/pubmed/24330808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-55
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