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Molecular Pathways: Resistance to Kinase Inhibitors and Implications for Therapeutic Strategies

The development of targeted therapies has revolutionized the treatment of cancer patients. The identification of ‘druggable’ oncogenic kinases and the creation of small molecule inhibitors designed to specifically target these mutant kinases has become an important therapeutic paradigm across severa...

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Detalhes bibliográficos
Main Authors: Lovly, Christine M., Shaw, Alice T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029617/
https://ncbi.nlm.nih.gov/pubmed/24789032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1610
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