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Aberrant DNA methyltransferase expression in pancreatic ductal adenocarcinoma development and progression
BACKGROUND: Altered gene methylation, regulated by DNA methyltransferases (DNMT) 1, 3a and 3b, contributes to tumorigenesis. However, the role of DNMT in pancreatic ductal adenocarcinoma (PDAC) remains unknown. METHODS: Expression of DNMT 1, 3a and 3b was detected in 88 Pancreatic ductal adenocarcin...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4029463/ https://ncbi.nlm.nih.gov/pubmed/24423239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-86 |
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