Aberrant DNA methyltransferase expression in pancreatic ductal adenocarcinoma development and progression

BACKGROUND: Altered gene methylation, regulated by DNA methyltransferases (DNMT) 1, 3a and 3b, contributes to tumorigenesis. However, the role of DNMT in pancreatic ductal adenocarcinoma (PDAC) remains unknown. METHODS: Expression of DNMT 1, 3a and 3b was detected in 88 Pancreatic ductal adenocarcin...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gao, Jun, Wang, Lihua, Xu, Jinkang, Zheng, Jianming, Man, Xiaohua, Wu, Hongyu, Jin, Jin, Wang, Kaixuan, Xiao, Huasheng, Li, Shude, Li, Zhaoshen
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029463/
https://ncbi.nlm.nih.gov/pubmed/24423239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-86
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