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Phase I study of sorafenib in combination with everolimus (RAD001) in patients with advanced neuroendocrine tumors

PURPOSE: Sorafenib and everolimus are both active against neuroendocrine tumors (NET). Because of potential synergy between VEGF pathway and mTOR inhibitors, we performed a phase I study to evaluate the safety and feasibility of combining sorafenib and everolimus in patients with advanced NET. METHO...

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Détails bibliographiques
Auteurs principaux: Chan, Jennifer A., Mayer, Robert J., Jackson, Nadine, Malinowski, Paige, Regan, Eileen, Kulke, Matthew H.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029418/
https://ncbi.nlm.nih.gov/pubmed/23475104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2118-9
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