Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer’s disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypo...

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Bibliographische Detailangaben
Hauptverfasser: Velazquez, Ramon, Ash, Jessica A., Powers, Brian E., Kelley, Christy M., Strawderman, Myla, Luscher, Zoe I., Ginsberg, Stephen D., Mufson, Elliott J., Strupp, Barbara J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029409/
https://ncbi.nlm.nih.gov/pubmed/23643842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.04.016
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