Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer’s disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypo...

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Detalhes bibliográficos
Main Authors: Velazquez, Ramon, Ash, Jessica A., Powers, Brian E., Kelley, Christy M., Strawderman, Myla, Luscher, Zoe I., Ginsberg, Stephen D., Mufson, Elliott J., Strupp, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029409/
https://ncbi.nlm.nih.gov/pubmed/23643842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.04.016
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