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Visualization and probability-based scoring of structural variants within repetitive sequences

Motivation: Repetitive sequences account for approximately half of the human genome. Accurately ascertaining sequences in these regions with next generation sequencers is challenging, and requires a different set of analytical techniques than for reads originating from unique sequences. Complicating...

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Main Authors: Halper-Stromberg, Eitan, Steranka, Jared, Burns, Kathleen H., Sabunciyan, Sarven, Irizarry, Rafael A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029030/
https://ncbi.nlm.nih.gov/pubmed/24501098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu054
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