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Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila

The border cells of Drosophila are a model system for coordinated cell migration. Ecdysone signaling has been shown to act as the timing signal to initiate the migration process. Here we find that mutations in phantom (phm), encoding an enzyme in the ecdysone biosynthesis pathway, block border cell...

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Autors principals: Domanitskaya, Elena, Anllo, Lauren, Schüpbach, Trudi
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028970/
https://ncbi.nlm.nih.gov/pubmed/24373956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.12.013
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