SYK Regulates mTOR Signaling in AML

Spleen Tyrosine Kinase (SYK) was recently identified as a new target in acute myeloid leukemia (AML); however, its mechanistic role in this disease is poorly understood. Based on the known interaction between SYK and mTOR signaling in lymphoma, we hypothesized that SYK may regulate mTOR signaling in...

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Hlavní autoři: Carnevale, Julia, Ross, Linda, Puissant, Alexandre, Banerji, Versha, Stone, Richard M., DeAngelo, Daniel J., Ross, Kenneth N., Stegmaier, Kimberly
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028963/
https://ncbi.nlm.nih.gov/pubmed/23535559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.89
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