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Cholesterol level affects surface charge of lipid membranes in saline solution

Cholesterol is an important component of all biological membranes as well as drug delivery liposomes. We show here that increasing the level of cholesterol in a phospholipid membrane decreases surface charge in the physiological environment. Through molecular dynamics simulation we have shown that i...

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Bibliografski detalji
Glavni autori: Magarkar, Aniket, Dhawan, Vivek, Kallinteri, Paraskevi, Viitala, Tapani, Elmowafy, Mohammed, Róg, Tomasz, Bunker, Alex
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028897/
https://ncbi.nlm.nih.gov/pubmed/24845659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05005
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