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Akt inhibitors: mechanism of action and implications for anticancer therapeutics
Akt, better known as protein kinase B (PKB), is a serine/threonine-specific protein kinase which acts as mediator via PI3K/Akt pathway in many biological processes like glucose metabolism, apoptosis, cell differentiation and transcription. Akt1 gene amplification has been implicated in gastric carci...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028840/ https://ncbi.nlm.nih.gov/pubmed/24330834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-8-49 |
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