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The Role of Molecular Genetic Analysis in the Diagnosis of Primary Ciliary Dyskinesia

Rationale: Primary ciliary dyskinesia (PCD) is an autosomal recessive genetic disorder of motile cilia. The diagnosis of PCD has previously relied on ciliary analysis with transmission electron microscopy or video microscopy. However, patients with PCD may have normal ultrastructural appearance, and...

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Detalhes bibliográficos
Main Authors: Kim, Raymond H., A. Hall, David, Cutz, Ernest, Knowles, Michael R., Nelligan, Kathleen A., Nykamp, Keith, Zariwala, Maimoona A., Dell, Sharon D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028737/
https://ncbi.nlm.nih.gov/pubmed/24498942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201306-194OC
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