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Crowdsourcing Natural Products Discovery to Access Uncharted Dimensions of Fungal Metabolite Diversity()
A new Tolypocladium sp. was obtained through a crowdsourcing initiative. Triggering the expression of a silent biosynthetic pathway in this fungus was achieved through chemical epigenetics, culture medium manipulation, and co–culture to yield the unique polyketide–shikimate–NRPS–hybrid compound, max...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028707/ https://ncbi.nlm.nih.gov/pubmed/24285637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201306549 |
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