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Adaptive mutation sequences reproduced by mismatch repair deficiency.

Adaptive reversions of a lac frameshift mutation in Escherichia coli are -1 deletions in small mononucleotide repeats, whereas growth-dependent reversions are heterogeneous. The adaptive mutations resemble instability of simple repeats, which, in hereditary colon cancer, in yeast, and in E. coli occ...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Longerich, S, Galloway, A M, Harris, R S, Wong, C, Rosenberg, S M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40287/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12017
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