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Descending Facilitatory Pathways From the Rostroventromedial Medulla Mediate Naloxone-precipitated Withdrawal in Morphine-Dependent Rats

Opioids produce analgesic effects and extended use can produce physical dependence in both humans and animals. Dependence to opiates can be demonstrated by either termination of drug administration or through precipitation of the withdrawal syndrome by opiate antagonists. Key features of the opiate...

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Autors principals: Vera-Portocarrero, Louis P., Ossipov, Michael H, Lai, Josephine, King, Tamara, Porreca, Frank
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028695/
https://ncbi.nlm.nih.gov/pubmed/21354865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2010.12.007
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