Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: implications in ADPKD cell proliferation

In autosomal dominant polycystic kidney disease (ADPKD), renal cyst development and enlargement, as well as cell growth, are associated with alterations in several pathways, including cAMP and activator protein 1 (AP1) signalling. However, the precise mechanism by which these molecules stimulate cel...

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Huvudupphovsmän: Aguiari, Gianluca, Bizzarri, Fabiana, Bonon, Anna, Mangolini, Alessandra, Magri, Eros, Pedriali, Massimo, Querzoli, Patrizia, Somlo, Stefan, Harris, Peter C., Catizone, Luigi, del Senno, Laura
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028691/
https://ncbi.nlm.nih.gov/pubmed/22570239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0902-3
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