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Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: implications in ADPKD cell proliferation

In autosomal dominant polycystic kidney disease (ADPKD), renal cyst development and enlargement, as well as cell growth, are associated with alterations in several pathways, including cAMP and activator protein 1 (AP1) signalling. However, the precise mechanism by which these molecules stimulate cel...

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Detalhes bibliográficos
Main Authors: Aguiari, Gianluca, Bizzarri, Fabiana, Bonon, Anna, Mangolini, Alessandra, Magri, Eros, Pedriali, Massimo, Querzoli, Patrizia, Somlo, Stefan, Harris, Peter C., Catizone, Luigi, del Senno, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028691/
https://ncbi.nlm.nih.gov/pubmed/22570239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0902-3
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