B-cell activating factor (BAFF) and BAFF-R levels correlate with B-cell subset activation and redistribution in controlled human malaria infection

Characteristic features of Plasmodium falciparum malaria are polyclonal B-cell activation and an altered composition of the blood B-cell compartment, including expansion of CD21−CD27− atypical memory B-cells. B-cell activating factor (BAFF) is a key cytokine in B-cell homeostasis, but its potential...

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Bibliographic Details
Main Authors: Scholzen, Anja, Teirlinck, Anne C., Bijker, Else M., Roestenberg, Meta, Hermsen, Cornelus C., Hoffman, Stephen L., Sauerwein, Robert W.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028688/
https://ncbi.nlm.nih.gov/pubmed/24646735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302960
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