Calcium Release from Intra-Axonal Endoplasmic Reticulum Leads to Axon Degeneration through Mitochondrial Dysfunction

Axonal degeneration represents an early pathological event in neurodegeneration, constituting an important target for neuroprotection. Regardless of the initial injury, which could be toxic, mechanical, metabolic, or genetic, degeneration of axons shares a common mechanism involving mitochondrial dy...

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Detalhes bibliográficos
Main Authors: Villegas, Rosario, Martinez, Nicolas W., Lillo, Jorge, Pihan, Phillipe, Hernandez, Diego, Twiss, Jeffery L., Court, Felipe A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028495/
https://ncbi.nlm.nih.gov/pubmed/24849352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4784-13.2014
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