Nod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids

BACKGROUND & AIMS: Chronic liver disease is characterized by fibrosis that may progress to cirrhosis. Nucleotide oligomerization domain 2 (Nod2), a member of the Nod-like receptor (NLR) family of intracellular immune receptors, plays an important role in the defense against bacterial infection t...

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Main Authors: Wang, Lirui, Hartmann, Phillipp, Haimerl, Michael, Bathena, Sai P., Sjöwall, Christopher, Almer, Sven, Alnouti, Yazen, Hofmann, Alan F., Schnabl, Bernd
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028388/
https://ncbi.nlm.nih.gov/pubmed/24560660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.02.012
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