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The pore-forming bacterial effector, VopQ, halts autophagic turnover

Vibrio parahemolyticus Type III effector VopQ is both necessary and sufficient to induce autophagy within one hour of infection. We demonstrated that VopQ interacts with the V(o) domain of the conserved vacuolar H(+)-ATPase. Membrane-associated VopQ subsequently forms pores in the membranes of acidi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sreelatha, Anju, Orth, Kim, Starai, Vincent J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028346/
https://ncbi.nlm.nih.gov/pubmed/24145145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26449
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