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The pore-forming bacterial effector, VopQ, halts autophagic turnover
Vibrio parahemolyticus Type III effector VopQ is both necessary and sufficient to induce autophagy within one hour of infection. We demonstrated that VopQ interacts with the V(o) domain of the conserved vacuolar H(+)-ATPase. Membrane-associated VopQ subsequently forms pores in the membranes of acidi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028346/ https://ncbi.nlm.nih.gov/pubmed/24145145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26449 |
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