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Impact of Histidine Residues on the Transmembrane Helices of Viroporins

The role of histidine in channel-forming transmembrane (TM) helices was investigated by comparing the transmembrane helices from Virus protein ‘u’ (Vpu) and the M2 proton channel. Both proteins are members of the viroporin family of small membrane proteins that exhibit ion channel activity, and have...

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Autori principali: Wang, Yan, Park, Sang Ho, Tian, Ye, Opella, Stanley J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028331/
https://ncbi.nlm.nih.gov/pubmed/24102567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09687688.2013.842657
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