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Comparative NMR Studies Demonstrate Profound Differences Between Two Viroporins: p7 of HCV and Vpu of HIV-1

The p7 protein from hepatitis C virus and the Vpu protein from HIV-1 are members of the viroporin family of small viral membrane proteins. It is essential to determine their structures in order to obtain an understanding of their molecular mechanisms and to develop new classes of anti-viral drugs. B...

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Main Authors: Cook, Gabriel A., Zhang, Hua, Park, Sang Ho, Wang, Yan, Opella, Stanley J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005007/
https://ncbi.nlm.nih.gov/pubmed/20727848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.08.005
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