Serum Amyloid A Induces NLRP-3-Mediated IL-1β Secretion in Neutrophils

BACKGROUND/AIMS: Serum amyloid A (SAA) is an acute phase reactant with significant immunological activities, including effects on cytokine synthesis and neutrophil chemotaxis. Neutrophils can also release cytokines with proinflammatory properties. IL-1β is a key proinflammatory cytokine, the secreti...

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Bibliographic Details
Main Authors: Migita, Kiyoshi, Izumi, Yasumori, Jiuchi, Yuka, Kozuru, Hideko, Kawahara, Chieko, Nakamura, Minoru, Nakamura, Tadashi, Agematsu, Kazunaga, Masumoto, Junya, Yasunami, Michio, Kawakami, Atsushi, Eguchi, Katsumi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028190/
https://ncbi.nlm.nih.gov/pubmed/24846290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096703
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