Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells

BACKGROUND: Genetic alterations, including the overexpression of epidermal growth factor receptor (EGFR), play a crucial role in ovarian carcinogenesis. To date, EGFR targeting has shown limited antitumor effects in ovarian cancer when administered as monotherapy. We previously identified platelet-a...

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Detalhes bibliográficos
Main Authors: Yu, Yi, Zhang, Mingxing, Zhang, Xiaoyan, Cai, Qingqing, Hong, Shanshan, Jiang, Wei, Xu, Congjian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028110/
https://ncbi.nlm.nih.gov/pubmed/24886678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-39
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