Epidermal growth factor induces platelet-activating factor production through receptors transactivation and cytosolic phospholipase A(2) in ovarian cancer cells

BACKGROUND: Among the pro-inflammatory lipid mediators, platelet-activating factor (PAF) is a major primary and secondary messenger that binds to the PAF-receptor (PAFR). Epidermal growth factor (EGF) is a polypeptide growth factor that binds to the EGF-receptor (EGFR). Evidence suggests that both P...

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Autori principali: Yu, Yi, Zhang, Xiaoyan, Hong, Shanshan, Zhang, Mingxing, Cai, Qingqing, Jiang, Wei, Xu, Congjian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005630/
https://ncbi.nlm.nih.gov/pubmed/24721622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-39
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