Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential

Tumors exhibit numerous recurrent hemizygous focal deletions that contain no known tumor suppressors and are poorly understood. To investigate whether these regions contribute to tumorigenesis, we searched genetically for genes with cancer-relevant properties within these hemizygous deletions. We id...

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Detalhes bibliográficos
Main Authors: Solimini, Nicole L., Xu, Qikai, Mermel, Craig H., Liang, Anthony C., Schlabach, Michael R., Luo, Ji, Burrows, Anna E., Anselmo, Anthony N., Bredemeyer, Andrea L., Li, Mamie Z., Beroukhim, Rameen, Meyerson, Matthew, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027969/
https://ncbi.nlm.nih.gov/pubmed/22628553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1219580
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