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Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma

AIM: To analyze the genetic and epigenetic alterations of RUNX3 gene, a potential putative tumor suppressor gene, in hepatocellular carcinoma (HCC). METHODS: PCR-based loss of heterozygosity (LOH) detection, analysis of mutation with PCR-single strand conformational polymorphism (SSCP) and sequencin...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Xiao, Wen-Hua, Liu, Wei-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724901/
https://ncbi.nlm.nih.gov/pubmed/14760761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i3.376
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