Design, Synthesis, and Optimization of Balanced Dual NK(1)/NK(3) Receptor Antagonists

[Image: see text] In connection with a program directed at potent and balanced dual NK(1)/NK(3) receptor ligands, a focused exploration of an original class of peptidomimetic derivatives was performed. The rational design and molecular hybridization of a novel phenylalanine core series was achieved...

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Bibliografski detalji
Glavni autori: Hanessian, Stephen, Jennequin, Thomas, Boyer, Nicolas, Babonneau, Vincent, Soma, Udaykumar, Mannoury la Cour, Clotilde, Millan, Mark J., De Nanteuil, Guillaume
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027792/
https://ncbi.nlm.nih.gov/pubmed/24900878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400528y
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