Dual RXR Agonists and RAR Antagonists Based on the Stilbene Retinoid Scaffold

[Image: see text] Arotinoids containing a C5,C8-diphenylnaphthalene-2-yl ring linked to a (C3-halogenated) benzoic acid via an ethenyl connector (but not the corresponding naphthamides), which are prepared by Horner–Wadsworth–Emmons reaction of naphthaldehydes and benzylphosphonates, display the rat...

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Detalhes bibliográficos
Main Authors: Martínez, Claudio, Lieb, Michele, Álvarez, Susana, Rodríguez-Barrios, Fátima, Álvarez, Rosana, Khanwalkar, Harshal, Gronemeyer, Hinrich, de Lera, Angel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027779/
https://ncbi.nlm.nih.gov/pubmed/24900875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400521f
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