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Analogues of the Natural Product Sinefungin as Inhibitors of EHMT1 and EHMT2
[Image: see text] A series of analogues of the natural product sinefungin lacking the amino acid moiety was synthesized and probed for their ability to inhibit EHMT1 and EHMT2. This study led to inhibitors 3b and 4d of methyltransferase activity of EHMT1 and EHMT2 and it demonstrates that such analo...
Sparad:
| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Chemical
Society
2014
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027773/ https://ncbi.nlm.nih.gov/pubmed/24900829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4002503 |
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