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Rationale for Therapeutic Silencing of Alpha-Synuclein in Parkinson’s Disease

The purpose of this paper is to provide the rationale for therapeutic silencing of the alpha-synuclein gene (SNCA) in Parkinson’s disease (PD). The paper reviews the public health significance of PD; the causal links between rare SNCA variants and familial PD; the association of common SNCA variants...

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Bibliografiske detaljer
Hovedforfatter: Maraganore, Demetrius M.
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Movement Disorder Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027709/
https://ncbi.nlm.nih.gov/pubmed/24868385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14802/jmd.11001
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