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Rationale for Therapeutic Silencing of Alpha-Synuclein in Parkinson’s Disease

The purpose of this paper is to provide the rationale for therapeutic silencing of the alpha-synuclein gene (SNCA) in Parkinson’s disease (PD). The paper reviews the public health significance of PD; the causal links between rare SNCA variants and familial PD; the association of common SNCA variants...

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Detalhes bibliográficos
Autor principal: Maraganore, Demetrius M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Movement Disorder Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027709/
https://ncbi.nlm.nih.gov/pubmed/24868385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14802/jmd.11001
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