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Synthesis and Antiplasmodial and Antimycobacterial Evaluation of New Nitroimidazole and Nitroimidazooxazine Derivatives

[Image: see text] The synthesis and antiplasmodial and antimycobacterial evaluation of two new series of nitroimidazole and nitroimidazooxazine derivatives is described. The majority of these compounds, especially hybrids 9d, 9f, and 14b, exhibited potent activity against the chloroquine-resistant K...

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Detalhes bibliográficos
Main Authors: Tukulula, Matshawandile, Sharma, Rajni-Kant, Meurillon, Maïa, Mahajan, Aman, Naran, Krupa, Warner, Digby, Huang, Jianxing, Mekonnen, Belew, Chibale, Kelly
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027538/
https://ncbi.nlm.nih.gov/pubmed/24900574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300362a
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