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Novel (64)Cu-Labeled CUDC-101 for in Vivo PET Imaging of Histone Deacetylases

[Image: see text] We report the design, synthesis, and biological evaluation of a (64)Cu-labeled histone deacetylase (HDAC) imaging probe, which was obtained by introduction of metal chelator through click reaction of HDAC inhibitor CUDC-101 and then radiolabeled with (64)Cu. The resulting (64)Cu-la...

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Bibliografiske detaljer
Main Authors: Meng, Qingqing, Li, Feng, Jiang, Sheng, Li, Zheng
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2013
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027442/
https://ncbi.nlm.nih.gov/pubmed/24900760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400191z
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