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Inferring probabilistic miRNA–mRNA interaction signatures in cancers: a role-switch approach
Aberrant microRNA (miRNA) expression is implicated in tumorigenesis. The underlying mechanisms are unclear because the regulations of each miRNA on potentially hundreds of mRNAs are sample specific. We describe a novel approach to infer Probabilistic MiRNA–mRNA Interaction Signature (‘ProMISe’) from...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027195/ https://ncbi.nlm.nih.gov/pubmed/24609385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku182 |
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