[(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor

[Image: see text] Rational modification of the potent calcitonin gene-related peptide (CGRP) receptor antagonist MK-3207 led to a series of analogues with enhanced CNS penetrance and a convenient chemical handle for introduction of a radiolabel. A number of (11)C-tracers were synthesized and evaluat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bell, Ian M., Gallicchio, Steven N., Stump, Craig A., Bruno, Joseph G., Fan, Hong, Gantert, Liza T., Hostetler, Eric D., Kemmerer, Amanda L., McWherter, Melody, Moore, Eric L., Mosser, Scott D., Purcell, Mona L., Riffel, Kerry, Salvatore, Christopher A., Sanabria-Bohórquez, Sandra, Staas, Donnette D., White, Rebecca B., Williams, Mangay, Zartman, C. Blair, Cook, Jacquelynn J., Hargreaves, Richard J., Kane, Stefanie A., Graham, Samuel L., Selnick, Harold G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027146/
https://ncbi.nlm.nih.gov/pubmed/24900761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400199p
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados