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Inhibition of Plasmodium falciparum malaria using antisense oligodeoxynucleotides.

We studied inhibition of growth of the malaria parasite Plasmodium falciparum in in vitro culture using antisense (AS) oligodeoxynucleotides (ODNs) against different target genes. W2 and W2mef strains of drug-resistant parasites were exposed to AS ODNs over 48 hr, and growth was determined by micros...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Barker, R H, Metelev, V, Rapaport, E, Zamecnik, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40268/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.514
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