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Clinical response to sunitinib as a multitargeted tyrosine-kinase inhibitor (TKI) in solid cancers: a review of clinical trials

Angiogenesis is an integral process in carcinogenesis, and molecular inhibitors of angiogenic factors are currently being tested as treatments for cancer. Sunitinib is an oral multitargeted tyrosine-kinase inhibitor that blocks activation through the stem cell-factor receptor (Kit) and platelet-deri...

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Detalhes bibliográficos
Main Authors: Kim, Sungkyoung, Ding, Wenping, Zhang, Lian, Tian, Wei, Chen, Siyu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026584/
https://ncbi.nlm.nih.gov/pubmed/24872713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S61388
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