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Molecular Dynamics Simulation Study of Conformational Changes of Transcription Factor TFIIS during RNA Polymerase II Transcriptional Arrest and Reactivation

Transcription factor IIS (TFIIS) is a protein known for catalyzing the cleavage reaction of the 3′-end of backtracked RNA transcript, allowing RNA polymerase II (Pol II) to reactivate the transcription process from the arrested state. Recent structural studies have provided a molecular basis of prot...

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Main Authors: Eun, Changsun, Ortiz-Sánchez, Juan Manuel, Da, Lintai, Wang, Dong, McCammon, J. Andrew
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026522/
https://ncbi.nlm.nih.gov/pubmed/24842057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097975
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