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Identification of the Key Differential Transcriptional Responses of Human Whole Blood Following TLR2 or TLR4 Ligation In-Vitro

The use of human whole blood for transcriptomic analysis has potential advantages over the use of isolated immune cells for studying the transcriptional response to pathogens and their products. Whole blood stimulation can be carried out in a laboratory without the expertise or equipment to isolate...

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Main Authors: Blankley, Simon, Graham, Christine M., Howes, Ashleigh, Bloom, Chloe I., Berry, Matthew P. R., Chaussabel, Damien, Pascual, Virginia, Banchereau, Jacques, Lipman, Marc, O’Garra, Anne
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026482/
https://ncbi.nlm.nih.gov/pubmed/24842522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097702
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