Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza

Transcriptional profiles and host response biomarkers are used increasingly to investigate the severity, subtype and pathogenesis of disease. We now describe whole blood mRNA signatures, local and systemic immune mediator concentrations in 131 adults hospitalised with influenza from which extensive...

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Vydáno v:Nat Immunol
Hlavní autoři: Dunning, Jake, Blankley, Simon, Hoang, Long T, Cox, Mike, Graham, Christine M, James, Philip L, Bloom, Chloe I, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Moffatt, Miriam F, O’Garra, Anne, Openshaw, Peter JM
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985949/
https://ncbi.nlm.nih.gov/pubmed/29777224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0111-5
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