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High frequency of rare variants with a moderate-to-high predicted biological effect in protocadherin genes of extremely obese
Relatively rare variants with a moderate-to-high biological effect may contribute to the genetic predisposition of common disorders. To investigate this for obesity, we performed exome sequencing for 30 young (mean age: 29.7 years) extremely obese Caucasian subjects (mean body mass index: 51.1 kg/m(...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026441/ https://ncbi.nlm.nih.gov/pubmed/24682882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-014-0399-1 |
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