Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice

CD146 is a newly identified endothelial biomarker that has been implicated in angiogenesis. Though in vitro angiogenic function of CD146 has been extensively reported, in vivo evidence is still lacking. To address this issue, we generated endothelial-specific CD146 knockout (CD146(EC-KO)) mice using...

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Hlavní autoři: Zeng, Qiqun, Wu, Zhenzhen, Duan, Hongxia, Jiang, Xuan, Tu, Tao, Lu, Di, Luo, Yongting, Wang, Ping, Song, Lina, Feng, Jing, Yang, Dongling, Yan, Xiyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026419/
https://ncbi.nlm.nih.gov/pubmed/24756564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0047-y
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