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The Quest for Selective Nox Inhibitors and Therapeutics: Challenges, Triumphs and Pitfalls
Significance: Numerous studies in animal models and human subjects corroborate that elevated levels of reactive oxygen species (ROS) play a pivotal role in the progression of multiple diseases. As a major source of ROS in many organ systems, the NADPH oxidase (Nox) has become a prime target for ther...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Mary Ann Liebert, Inc.
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026400/ https://ncbi.nlm.nih.gov/pubmed/24070014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5620 |
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