Pattern of BRCA1 Expression is a Potential Prognostic Biomarker in Resectable Pancreatic Ductal Adenocarcinoma

OBJECTIVES: The tumor suppressor BRCA1 is a nuclear-cytoplasmic shuttling protein that when in the nucleus is required for DNA repair whereas when in the cytoplasm is important in activating cell death processes. Although BRCA1 mutations have been shown to be associated with an increased risk of pan...

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Main Authors: Wang, Tong, Wentz, Sabrina C., Ausborn, Natalie L., Washington, M. Kay, Merchant, Nipun, Zhao, Zhiguo, Shyr, Yu, Chakravarthy, A. Bapsi, Xia, Fen
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026161/
https://ncbi.nlm.nih.gov/pubmed/23851432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e318287885c
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